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News & Events

Scrapie could breach the species barrier - 17/12/2014

Flock of sheep marked after drafting at the Ruminants Experimental Unit in Theix
INRA scientists have shown for the first time that the pathogens responsible for scrapie in small ruminants (prions) have the potential to convert the human prion protein from a healthy state to a...

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A new method for in vivo study of the virus that causes bronchiolitis - 03/10/2014

Bioluminescence détectée chez une souris infectée par le virus respiratoire syncytial
INRA research scientists, working in collaboration with Paris Public Hospitals (AP-HP) and the University of Versailles-Saint-Quentin-en-Yvelines, have developed a new method to study the virus tha...

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11am - room 800 - 26 June 2014

Seminar - Loredana Saveanu (Necker Hospital, Paris)

Dendritic cell processing antigens in the endosomal compartment
"The role of IRAP storage endosomes in dendritic cell biology"

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A new vaccine platform to protect against West Nile Virus - 10/06/2014

Research scientists in the Molecular Virology and Immunology Unit have developed a recombinant virus that procures partial protection against West Nile Virus in mice. This recombinant virus has pro...

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New live attenuated influenza vaccines - 18/07/2013

photo de microscopie du virus influenza
In the frame of the Carnot Institute for Animal health “ICSA”, within the “Molecular Virology and Immunology” unit, INRA’s researchers steered by Dr Bernard Delmas have identified mutations within...

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Towards the First Pediatric Vaccine against Bronchiolitis - 14/06/2013

Service de néonatologie au CHU Hôtel-Dieu de Nantes, Hôpital Mère et Enfant. Les bébés prématurés y restent en couveuse jusqu'à la date théorique de leur naissance.
INRA and its partner DBV Technologies were just granted €600 000 by the French National Research Agency (ANR) to coordinate their know-how and develop an innovative and non-invasive vaccine against...

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“Tailor-made” antiviral compounds to fight influenza A - 25/03/2013

“Tailor-made” antiviral compounds to fight influenza A
Scientists have identified on viral proteins the “nerve centres” which need to be targeted by therapeutic compounds in order to halt any proliferation that might cause influenza A. Using computer...

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About the Unit

The laboratory of Molecular Virology and Immunology (VIM-UR892) studies pathogens affecting farm animals.

Our research activities range from the molecular characterization of pathogens to host-defense mechanisms.

We are mainly interested in respiratory viruses in mammals and birds, fish viruses and bacteria, and non-conventional agents such as prions.

We study host-pathogen interactions in target species (swine, cattle, sheep, trout) or model species (mice, zebra fish).

Scientific issues:
1) Structure and expression of pathogen genomes
2) Structure-function relationships of macro-molecular complexes
3) Virulence-pathogenicity factors and escape from host defenses
4) Plasticity of host responses during evolution and development
5) Fighting strategies: vaccination and therapeutical approaches

The laboratory is organised around three main fields of interest:

  • Animal respiratory viruses: host-virus interactions, immunity
  • Prions
  • Fish infectiology

The laboratory also hosts the editorial team of the open access journal Veterinary Research.

Director: Sabine Riffault
Co-Director: Pierre Boudinot
Centre de Recherche de Jouy-en-Josas
F-78352 Jouy-en-Josas cedex