Know more

Our use of cookies

Cookies are a set of data stored on a user’s device when the user browses a web site. The data is in a file containing an ID number, the name of the server which deposited it and, in some cases, an expiry date. We use cookies to record information about your visit, language of preference, and other parameters on the site in order to optimise your next visit and make the site even more useful to you.

To improve your experience, we use cookies to store certain browsing information and provide secure navigation, and to collect statistics with a view to improve the site’s features. For a complete list of the cookies we use, download “Ghostery”, a free plug-in for browsers which can detect, and, in some cases, block cookies.

Ghostery is available here for free: https://www.ghostery.com/fr/products/

You can also visit the CNIL web site for instructions on how to configure your browser to manage cookie storage on your device.

In the case of third-party advertising cookies, you can also visit the following site: http://www.youronlinechoices.com/fr/controler-ses-cookies/, offered by digital advertising professionals within the European Digital Advertising Alliance (EDAA). From the site, you can deny or accept the cookies used by advertising professionals who are members.

It is also possible to block certain third-party cookies directly via publishers:

Cookie type

Means of blocking

Analytical and performance cookies

Realytics
Google Analytics
Spoteffects
Optimizely

Targeted advertising cookies

DoubleClick
Mediarithmics

The following types of cookies may be used on our websites:

Mandatory cookies

Functional cookies

Social media and advertising cookies

These cookies are needed to ensure the proper functioning of the site and cannot be disabled. They help ensure a secure connection and the basic availability of our website.

These cookies allow us to analyse site use in order to measure and optimise performance. They allow us to store your sign-in information and display the different components of our website in a more coherent way.

These cookies are used by advertising agencies such as Google and by social media sites such as LinkedIn and Facebook. Among other things, they allow pages to be shared on social media, the posting of comments, and the publication (on our site or elsewhere) of ads that reflect your centres of interest.

Our EZPublish content management system (CMS) uses CAS and PHP session cookies and the New Relic cookie for monitoring purposes (IP, response times).

These cookies are deleted at the end of the browsing session (when you log off or close your browser window)

Our EZPublish content management system (CMS) uses the XiTi cookie to measure traffic. Our service provider is AT Internet. This company stores data (IPs, date and time of access, length of the visit and pages viewed) for six months.

Our EZPublish content management system (CMS) does not use this type of cookie.

For more information about the cookies we use, contact INRA’s Data Protection Officer by email at cil-dpo@inra.fr or by post at:

INRA
24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal AgroParisTech Université Paris-Saclay

INRA GABI Unit

GABI : Génétique Animale et Biologie IntégrativeUnité Mixte de Recherche INRA - AgroParisTech

The National Observatory for Bovine Anomalies

National Observatory of Bovine Anomalies
© INRA
The appearance of genetic anomalies is inevitable. They result from certain random DNA mutations. Their eradication has become much easier with the recent progress in molecular tools. The most critical point is the observation of their emergence and their clinical description which the ONAB coordinates at the national level.

Genetic anomalies emerge on a regular basis in livestock populations. Their appearance is practically inevitable.They are the result of DNA mutations that we cannot control. Even though they are not heterozygous (the mutation is then considered as being recessive), they can spread in a population over several generations without being recognized. Active surveillance is therefore necessary to detect these emerging abnormalities remembering that these first cases are detected late and are always made after the original mutation has occurred and spread throughout a population.

Searching for a mutation responsable for a specific anomaly requires several steps :

1) Identification of the emergence

2) Clinical description of the anomaly. This is a crutial step in order to guarentee the uniqueness of the pathology studied and to choose the appropriate direction for the genetic research

3) Sample collection (blood, ears, ....) from affected individuals in order to obtain DNA

4) Genetic analyses using genotyping and sequencing

Much progress has been made recently in genomics tools, providing a way to isolate a gene responsable for an anomaly much more rapidly. A diagnostic DNA test which allows the identification of diseases, carrier and non-carrier animals, is the only efficient way to eradicate anomalies in a population.

The first steps of observation of an emergence, clinical characterisation and sampling are the most difficult and require organisation and coordination and the intervention of many different actors on the field. Cécile Grohs (INRA) and Coralie Danchin (Institut de l'Elevage) are in charge of these observations coordinated by the National Observatory for Bovine Anomalies.

References

Capel C., Duchesne A. 2010 Du nouveau au sein de l’Observatoire National des Anomalies Bovines. BTIA, 132, 40.

Boichard D., Floriot S., Capel C., Duchesne A. 2010. Abord des anomalies génétiques bovines. Le Point Vétérinaire, 311, 66-69.

Ducos A., Manciaux L., Malafosse A., Eggen A. 2008. L'observatoire national des anomalies bovines : objectifs, actions mises en œuvre et premiers résultats. Journées Nationales GTV, Nantes, 29 mai 2008, 491-494.

Duchesne A., Ducos A., Manciaux L., Eggen A. 2006. Des marqueurs génétiques pour l’éradication des anomalies. BTIA, 120, 19-21.

See also