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Dernière mise à jour : Mai 2018

Menu Logo Principal AgroParisTech Université Paris-Saclay

INRA GABI Unit

GABI : Génétique Animale et Biologie IntégrativeUnité Mixte de Recherche INRA - AgroParisTech

The first publications from the GENENDURANCE project

The first publications from the GENENDURANCE project
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The collect of phentoyping and genotyping data within the GenEndurance project has been completed with the analysis of over 1000 Arab breed horses specialized in endurance races. The first publications on metabolomic phentoyping and cardiac factors for performance are available. One paper published by Plos One has already had an international impact by changing endurance race regulations by the International Equine Federation (FEI).

Context and stakes 

Sport and genetic selection of endurance race horses

Results

The first phentoyping results have been collected on the metabolic and cardiac specificity of endurance exercise along with their genetic component. A relatively high heritability (0.45) for heart recovery time (which is an important component of performance) was estimated within the framework of M Younes' doctoral studies.     

Perspectives

New selection criteria based on indirect heart aptitude could be used for Arab breed endurance horses. 

Valorization

Practical applications on the rules of elimination have already been considered by the FEI following the Plos One publication of July 2015.      

References

1: Luck MM, Le Moyec L, Barrey E, Triba MN, Bouchemal N, Savarin P, Robert C. Energetics of endurance exercise in young horses determined by nuclear magnetic resonance metabolomics. Front Physiol. 2015 Jul 15;6:198. eCollection 2015. PubMed PMID: 26347654; PubMed Central
PMCID: PMC4544308.

2: Younes M, Robert C, Cottin F, Barrey E. Speed and Cardiac Recovery Variables Predict the Probability of Elimination in Equine Endurance Events. PLoS One. 2015; Aug 31;10(8):e0137013. eCollection 2015. PubMed PMID: 26322506; PubMed Central PMCID: PMC4556447.
3: Le Moyec L, Robert C, Triba MN, Billat VL, Mata X, Schibler L, Barrey E. Protein catabolism and high lipid metabolism associated with long-distance
exercise are revealed by plasma NMR metabolomics in endurance horses. PLoS One. 2014 Mar 21;9(3):e90730. eCollection 2014. PubMed PMID: 24658361; PubMed Central PMCID: PMC3962349.
4: Younes M (2015) Facteurs de variation de l’activité cardiaque au repos, à l’effort et pendant la récupération chez le cheval d’endurance. Thèse doctorale Université Paris –Saclay , Ecole doctorale 577, Science de la vie et de la santé, 4 Décembre 2015, pp 163.