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INRA
24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal AgroParisTech Université Paris-Saclay

INRA GABI Unit

GABI : Génétique Animale et Biologie IntégrativeUnité Mixte de Recherche INRA - AgroParisTech

Genetics and Aquaculture

The main goal of our team is to contribute to the efficient management and use of aquaculture genetic resources

INRA GABI GenAqua Génétique Aquaculture
© INRA
Our research is focused around two main areas: the establishment and improvement of domestic fish farming stocks and the impact of domestication and restocking on the diversity of natural populations.

An important part of our work is dedicated to the analysis of the genetic determinism of traits and acquiring knowledge on the trout genome. Our team is active in the management of genetic resources and the optimization and evolution of aquaculture selection schemes.

► Genetic analysis of traits

  • Traits for adaptation and response to stress: our objective is to test the relevance and the genetic variability of potential criteria for adaptation. We exploit the ecological and genetic proximity of wild and domestic populations available in the two species studied (trout and sea bass). Besides the variability of adaptation traits with a farming finality (farming in captivity), our objective is to study the evolution of the genetic and behavioral variability of newly domesticated populations intended for restocking (common trout).
  • Traits for disease resistance: the two main models studied are a viral disease (Viral Hemorrhagic Septicemia or VHS) and a bacterial disease (flavobacteriosis). Our ambition is to gain knowledge on the genetic architecture of resistance, the understanding of the mechanisms involved and their variability and, in particular, on the identification of the components of the immune response, which are today poorly understood in the fish. We will use quantitative genetics, structural and gene candidate approaches.
  • Aptitude of feed use: this project is developed in partnership with the center of competitiveness for Fish Products. After characterizing the genetic variability of animals fed with plant-based feed, we will study the genotype x feed interactions and identify the genetic groups that possess extreme characteristics. Then QTL mapping and functional analysis will be performed.

► Knowledge on the trout genome

We contribute to the development of mapping tools in the rainbow trout via our studies on the response to pathogens and our generic studies led within the framework of the international consortium, cGRASP (Consortium for Genomic Research on All Salmonids Project).

► Management of aquaculture genetic resources

Ongoing studies concern the optimization of selection schemes and provide information on how to introduce partial genealogical information in the selection schemes on 25 second generations (Prosper+) in the case of carcass cutting yield, fish quality and disease resistance traits, with prospective studies on the identification of selection objectives for tomorrow within the project COSADD (a part ot the ANR program "Agriculture and Sustainable Development") and a research group bringing together scientists working on the improvement of fish entitled GDR "Genetic improvement for sustainable aquaculture").

Another aspect of the studies investigates the effects of domestication in farming situations and natural environments.

The GenAqua team has expertise in: population genetics, quantitative and molecular genetics (structural and functional). This expertise is reinforced within GABI via methodological exchanges and within the Animal Genetics division via partnerships with geneticists, in particular in the prospective field of genetic variance for plasticity.

Our projects are led in association with the IFREMER (French Research Institute for the Exploration of the Sea) team at Palavas, and thanks to continued support for studies on the sea bass and trout, two biological and aquaculture complementary models and to the renewal of the research group GDR "Genetic Improvement for Sustainable Aquaculture".

On the national level, we already work with pathologists and immunologists of the Animal Health division, physiologists with expertise on growth, adaptation and nutrition of the Animal Physiology and Farming Systems (PHASE) division, ecologists belonging to the Forest, Grasslands and Freshwater Ecology (EFPA) division and behavioral scientists belonging to IFREMER (French Research Institute for the Exploration of the Sea). These relationships provide us access to new phenotypes. We also have partnerships with the aquaculture sector on several projects associating the industry i.e. the SYSAAF (French professional association for selection in aquaculture and poultry farming) and private companies.

Our network of European partnerships is diverse and has been developed in the field of adaptation to the environment and disease resistance with the AQUAFIRST project. To study the sea bass, we have also gained access to an excellent network of European professionals, through the research group GDR "Genetic Improvement for Sustainable Aquaculture" and European projects Heritabolum and COMPETUS and the BASSMAP consortium (sea bass genomics).