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24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal AgroParisTech Université Paris-Saclay


GABI : Génétique Animale et Biologie IntégrativeUnité Mixte de Recherche INRA - AgroParisTech


Recent publications

Boushaba N, Boujenane I, Moazami-Goudarzi K, Flori L, Saïdi-Mehtar N, Tabet-Aoul N, Laloë D. 2019. Genetic diversity and relationships among six local cattle populations in semi-arid areas assessed by a bovine medium-density single nucleotide polymorphism data. Animal. 13, 8-14. 

Flori L, Moazami-Goudarzi K, Alary V, Araba A, Boujenane I, Boushaba N, Casabianca F, Casu S, Ciampolini R, Coeur D'acier A, Coquelle C, Delgado JV, El-Beltagi A, Hadjipavlou G, Jousselin E, Landi V, Lauvie A, Lecomte P, Ligda C, Marinthe C, Martinez A, Mastrangelo S, Menni D, Moulin CH, Osman MA, Pineau O, Portolano B, Rodellar C, Saidi-Mehtar N, Sechi T, Sempere G, Thevenon S, Tsiokos D, Laloë D, Gautier M. 2019. A genomic map of climate adaptation in Mediterranean cattle breeds. Mol Ecol. in press

Gobé C, El Zaiat M, Meunier N, André M, Sellem E, Congar P, Jouneau L, Allais-Bonnet A, Naciri I, Passet B, Pailhoux E, Pannetier M. 2019. Dual role of DMXL2 in olfactory information transmission and the first wave of spermatogenesis. PLoS Genet. 15,  e1007909

Hirsch TZ, Martin-Lanneree S, Reine , Hernandez-Rapp J, Herzog L, Dron M, Privat N, Passet B, Halliez S, Villa-Diaz A, Lacroux C, Klein V, Haik S, Andreoletti O, Torres JM, Vilotte JL, Beringue V, Mouillet-Richard S. 2019. Epigenetic control of the Notch and Eph signaling pathways by the prion protein: implications for prion diseases.  Mol Neurobiol. 56, 2159-2173


Caillot N, Bouley J, Jain M, Mariano S, Luce S, Horiot S, Airouche S, Beuraud C, Beauvallet C, Devillier P, Chollet-Martin S, Kellenberger,  C, Mascarell L, Chabre H, Batard T, Nony E, Lombardi V, Baron-Bodo V, Moingeon P. 2017. Sialylated Fetuin-A as a candidate predictive biomarker for successful grass pollen allergen immunotherapy. J Allergy Clin Immunol. 140, 759-770.

Dewaele A, Persuy MA, Badonnel K, Meunier N, Durieux D, Castille J, Favreau-Peigne A, Baly C. 2018. Chronic perinatal odour exposure with heptaldehyde affects odour sensitivity and olfactory system homeostasis in preweaning mice. Behav Brain Res. 347, 414-424

Duchesne A, Vaiman A, Castille J, Beauvallet C, Gaignard P, Floriot S, Rodriguez S, Vilotte M, Boulanger L, Passet B, Albaric O, Guillaume F, Boukadiri A, Richard L, Bertaud M, Timsit E, Guatteo R, Jaffrézic F, Calvel P, Helary L, Mahla R, Esquerré D, Péchoux C, Liuu S, Vallat JM, Boichard D, Slama A, Vilotte JL. 2017. Bovine and murine models highlight novel roles for SLC25A46 in mitochondrial dynamics and metabolism, with implications for human and animal health. PLoS Genet. 13, e1006597

Gilbert H, Billon Y, Brossard L, Faure J, Gatellier P, Gondret F, Labussière E, Lebret B, Lefaucheur L, Le Floch N, Louveau I, Merlot E, Meunier-Salaün MC, Montagne L, Mormede P, Renaudeau D, Riquet J, Rogel-Gaillard C, van Milgen J, Vincent A, Noblet J. 2017. Review: divergent selection for residual feed intake in the growing pig. Animal. ahead of printMartin-Lannerée S, Halliez S, Hirsch TZ, Hernandez-Rapp J, Passet B, Tomkiewicz C, Villa-Diaz A, Torres JM, Launay JM, Béringue V, Vilotte JL, Mouillet-Richard S. 2017. The cellular prion protein controls notch signaling in neural stem/progenitor cells. Stem Cells. 35, 754-795

Ilaslan E, Calvel P, Nowak D, Szarras-Czapnik M, Slowikowska-Hilczer J, Spik A, Sararols P, Nef S, Jaruzelska J, Kusz-Zamelczyk K. 2018. A case of two sisters suffering from 46,XY gonadal dysgenesis and carrying a mutation of a novel candidate sex-determining Gene STARD8 on the X chromosome. Sex Dev. 12, 191-195

Le Dur A, Lan Laı T, Stinnakre MG, Laisne A, Chenais N, Rakotobe S, Passet B, Reine F, Soulier S, Herzog L, Tilly G, Rezaei H, Beringue V, Vilotte JL, Laude H. 2017.  Divergent prion strain evolution driven by PrPC expression level in transgenic mice. Nat Comm. 8, 14170

Neirijnck Y, Calvel P, Kilcoyne KR, Kühne F, Stévant I, Griffeth RJ, Pitetti JL, Andric SA, Hu MC, Pralong F, Smith LB, Nef S. 2018. Insulin and IGF1 receptors are essential for the development and steroidogenic function of adult Leydig cells. FASEB J. 32, 3321-3335


Allais-Bonnet A, Castille J, Pannetier M, Passet B, Elzaiat M, Andre M, Montazer-Torbati F, Moazami-Goudarzi K, Vilotte JL, Pailhoux E. 2016. A specific role for PRND in goat foetal Leydig cells is suggested by prion family gene expression during gonad development in goats and mice.  Febs Open Bio. 6, 4-156

Ducat A, Doridot L, Calicchio R, Méhats C, Vilotte JL, Castille J, Barbaux S, Couderc B, Jacques S, Letourneur F, Buffat C, Le Grand F, Laissue P, Miralles F, Vaiman D. 2016. Endothelial cell dysfunction and cardiac hypertrophy in the STOX1 model of preeclampsia. Sci Rep. 6, 19196

Duchesne A, Grohs C, Michot P, Bertaud M, Boichard D, Floriot S, Capitan A. 2016. Du phénotype à la mutation causale : le cas des anomalies récessives bovines. Inra Prod Anim. 29, 319-328      

Gautier M, Moazami-Goudarzi K, Leveziel H, Grohs C, Rialle S, Kowalczyk R, Flori L . 2016. Deciphering the Wisent demographic and adaptive histories from individual whole-genome sequences. Molec Biol Evol. 33, 2801-2814

Grohs C, Duchesne A, Floriot S, Deloche MC, Boichard D, Ducos A, Danchin-Burge C. 2016. L’Observatoire National des Anomalies Bovines, son action et ses résultats pour une aide efficace à la gestion des anomalies génétiques. Inra Prod Anim. 29, 307-318  

Khalifé M, Reine F, Paquet-Fifield S, Castille J, Herzog L, Vilotte M, Moudjou M, Moazami-Goudarzi K, Makhzami S, Passet B, Andréoletti O, Vilette D, Laude H, Béringue V, Vilotte JL. 2016. Mutated but Not Deleted Ovine PrPC N-Terminal Polybasic Region Strongly Interferes with Prion Propagation in Transgenic Mice. J Virol. 90, 1638-1646

Martin-Lannerée S, Halliez S, Hirsch TZ, Hernandez-Rapp J, Passet B, Tomkiewicz C, Villa-Diaz A, Torres JM, Launay JM, Béringue V, Vilotte JL, Mouillet-Richard S. 2016. The cellular prion protein controls Notch signalling in neural stem / progenitor cells. Stem Cells. ahead of print

Previous publications

Daniel-Carlier N, Sawafta A, Passet B, Thépot D, Leroux-Coyau M, Lefèvre F, Houdebine LM, Jolivet G. 2013. Viral infection resistance conferred on mice by siRNA transgenesis. Transgenic Res. 22, 489-500

Doridot L, Châtre L, Ducat A, Vilotte JL, Lombès A, Méhats C, Barbaux S, Calicchio R, Ricchetti M, Vaiman D. 2014. Nitroso-redox balance and mitochondrial homeostasis are regulated by STOX1, a pre-eclampsia-associated gene. Antioxid Redox Signal. 21, 819-834

Doridot L., Passet B., Mehats C., Rigourd V., Barbaux S., Ducat A., Mondon F., Vilotte M., Castille J., Breuiller-Fouche M., Daniel N., le Provost F., Bauchet A.L., Baudrie V., Hertig A., Buffat C., Simeoni U., Germain G., Vilotte J.L., Vaiman D. 2013. Preeclampsia-Like Symptoms Induced in Mice by Fetoplacental Expression of STOX1 Are Reversed by Aspirin Treatment. Hypertension 61,662-668

Fares-Taie L, Gerber S, Tawara A, Ramirez-Miranda A, Douet JY, Verdin H, Guilloux A, Zenteno JC, Kondo H, Moisset H, Passet B, Yamamoto K, Iwai M, Tanaka T, Nakamura Y, Kimura W, Bole-Feysot C, Vilotte M, Odent S, Vilotte JL, Munnich A, Regnier A, Chassaing N, De Baere E, Raymond-Letron I, Kaplan J, Calvas P, Roche O, Rozet JM. 2015. Submicroscopic deletions at 13q32.1 cause congenital microcoria. Am J Hum Genet. 96, 631- 639

Flori L, Thevenon S, Dayo G-K,Senou M, Sylla S, Berthier D, Moazami-Goudarzi K, Gautier M. 2014. Adaptative admixture in the west African bovine hybrid zone insight from the borgou population. Mol Ecol . 23, 3241-3257

Floriot S, Vesque C, Rodriguez S, Bourgain-Guglielmetti F, Karaiskou A, Gautier M, Duchesne A, Barbey S, Fritz S, Vasilescu A, Bertaud M, Moudjou M, Halliez S, Cormier-Daire V, El Hokayem J, Nigg EA, Manciaux L, Guatteo R, Cesbron N, Toutirais G, Eggen A, Schneider-Maunoury S, Boichard D, Sobczak-Thépot J, Schibler L. 2015. C-Nap1 mutation affects centriole cohesion and is associated with a Seckel-like syndrome in cattle. Nat Commun. 6, 6894

Halliez S, Chesnais N, Mallucci G, Vilotte M, Langevin C, Jaumain E, Laude H, Vilotte JL, Beringue V. 2013. Targeted knock-down of cellular prion protein expression in myelinating Schwann cells does not alter mouse prion pathogenesis. J Gen Virol. 94, 1435-1440

Halliez S, Martin-Lanneree S, Passet B, Hernandez-Rapp J, Castille J, Urien C, Chat S, Laude H, Vilotte JL, Mouillet-Richard S, Beringue V. 2015. Prion protein localizes at the ciliary base during neural and cardiovascular development, and its depletion affects α-tubulin post-translational modifications. Sci Rep. 5, 17146

Halliez S, Passet B, Martin-Lannerée S, Hernandez-Rapp J, Laude H, Mouillet-Richard S, Vilotte JL, Béringue V. To develop with or without the prion protein. Front Cell Dev Biol. 2, 58

Halliez S, Reine F, Herzog L, Jaumain E, Haïk S, Rezaei H, Vilotte JL, Laude H, Béringue V. 2014. Accelerated, spleen-based titration of variant Creutzfeldt-Jakob disease infectivity in transgenic mice expressing human prion protein with sensitivity comparable to that of survival time bioassay. J Virol. 88, 8678- 8686

Jolivet G, Braud S, DaSilva B, Passet B, Harscoët E, Viglietta C, Gautier T, Lagrost L, Daniel-Carlier N, Houdebine LM, Harosh I. 2014. Induction of body weight loss through RNAi-knockdown of APOBEC1 gene expression in transgenic rabbits. PLoS ONE. 9, e106655

Lopez-Rios J, Duchesne A, Speziale D, Andrey G, Peterson KA, German P, Ünal E, Liu J, Floriot S, Barbey S, Gallard Y, Müller-Gerbl M, Courtney AD, Klopp C, Rodriguez S, Ivanek R, Beisel C, Wicking C, Iber D, Robert B, McMahon AP, Duboule D, Zeller R. 2014. Attenuated sensing of SHH by Ptch1underlies evolution of bovine limbs. Nature.  511, 46-51

Makzhami S, Passet B, Halliez S, Castille J, Moazami-Goudarzi K, Duchesne A, Vilotte M, Laude H, Mouillet-Richard S, Béringue V, Vaiman D, Vilotte JL. 2014. The prion protein family: a view from the placenta. Front Cell Dev Biol. 2, 35

Martin-Lannerée S, Hirsch TZ, Hernandez-Rapp J, Halliez S, Vilotte JL, Launay JM, Mouillet-Richard S. 2014. PrP(C) from stem cells to cancer. Front Cell Dev Biol. 2, 55

Mouillet-Ricard S, Vilotte JL. 2015. Promiscuous functions of the prion protein family. Front Cell Dev Biol. 3, 7

Passet B, Halliez S, Béringue V, Laude H, Vilotte JL.  2013. The prion protein family: Looking outside the central nervous system. Prion 7, 127-130

Sarradin P, Viglietta C, Limouzin C, Andreoletti O, Daniel-Carlier N, Barc C, Leroux-Coyau M, Berthon P, Chapuis J, Rossignol C, Gatti JL, Belghazi,M, Labas V, Vilotte JL, Beringue V, Lantier F, Laude H, Houdebine LM. 2015. Transgenic Rabbits Expressing Ovine PrP Are Susceptible to Scrapie. PLoS Pathogens. 11, e1005077

Wangkumhang P, Wilantho A, Shaw PJ, Flori L, Moazami-Goudarzi K, Gautier M, Duangjinda M, Assawamakin A, Tongsima S. 2015. Genetic analysis of Thai cattle reveals a Southeast Asian indicine ancestry. Peer J. 3, e1318