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Menu Logo Principal AgroParisTech Université Paris-Saclay

INRA GABI Unit

GABI : Génétique Animale et Biologie IntégrativeUnité Mixte de Recherche INRA - AgroParisTech

Michèle TIXIER-BOICHARD, Senior scientist

TIXIER-BOICHARD Michèle
Genetic diversity and characterisation of morphological mutations in chickens.

INRA, AgroParisTech UMR1313, Animal Genetics and Integrative Biology
Domaine de Vilvert, Bât 211, 78 352 Jouy-en-Josas Cedex
Phone : 33 1 34 65 21 78 ; Fax : 33 1 34 65 22 10

Email : michele.boichard(at)jouy.inra.fr

PSGen (Populations Statistics Genome) Team and Genomic Facilities Team

CV :

1977-1981 : veterinary studies (Alfort 1981)
1982 : master of sciences in quantitative genetics, Université Paris XI-Orsay,
1983 : Veterinary thesis (Faculté de Créteil)
1984 : PhD in quantitative genetics, Université Paris XI-Orsay,
1985 : INRA junior scientist – Animal Genetics Department
1999 : INRA senior scientist
2004-2006 : deputy president of INRA research center of Jouy-en-Josas
2006-2011 : scientific director of the ‘Bioresources – Ecology - Agronomy’ research fields at the Higher Education and Research ministry
2008-2009 : training at the Institute of Higher Studies for Science and Technology (IHEST). Member of IHEST fellows association.  

Research fields :

After conducting a selection experiment in laying hens, I became involved in characterization studies of genetic resources and molecular identification of morphological mutations in chickens. I am particularly interested by genes controlling plumage distribution and colour and got more recently involved in studies about chicken domestication.

Other activities :

President of the National Cryobank governing board.
Elected Vice-President of the World Poultry Science Association (WPSA)
Associated editor of BMC Genetics and World Poultry Science Journal. 

Recent publications and other productions :

Tixier-Boichard M., Lescourret F., 2015. Mieux utiliser la biodiversité pour réussir la transition agro-écologique : une synthèse de l’atelier ‘Utiliser la biodiversité’. Innovations Agronomiques 43, 41-50.

Tixier-Boichard M., Verrier E., Rognon X., Zerjal T, 2015. Farm animal genetic and genomic resources from an agroecological perspective. Front. Genet. 6:153. doi: 10.3389/fgene.2015.00153

Moro C., Cornette R., Vieaud A., Bruneau N., Gourichon D., Bed'hom B., Tixier-Boichard M. 2015. Quantitative Effect of a CNV on a Morphological Trait in Chickens. PLOS ONE 10: e0118706

Mignon-Grasteau S., Moreri, U., Narcy A, Rousseau X., Rodenburg T. B., Tixier-Boichard M., Zerjal T., 2015. Robustness to chronic heat stress in laying hens : a meta-analysis. Poultry Science 00:1–15, http://dx.doi.org/10.3382/ps/pev028

Wragg D, Mwacharo Jm, Alcalde Ja, Wang C, Han J, Gourichon D, Tixier-Boichard  M, Hanotte O, 2013. Endogenous Retrovirus EAV-HP Linked to Evolution of Blue Eggs in Mapuche Fowl. PLoS One, 8, e71393, doi:10.1371/journal.pone.0071393

Pham M. H, Berthouly-Salazar C., Tran X. H., Chang W. H.,. Crooijmans R. P. M. A, Lin D.Y., Hoang V. T., Lee Y. P., Tixier-Boichard M., Chen C- F. 2013. Genetic diversity of Vietnamese domestic chicken populations as decision-making support for conservation strategies. Animal Genetics, | doi: 10.1111/age.12045.

Chazara O, Chang Cs, Bruneau N, Benabdeljelil K, Kayang Bk, Loukou Ne, Osei-Amponsah R, Yapi-Gnaore V, Youssao Iak, Chen Cf, Pinard-Van Der Laan Mh, Tixier-Boichard  M, Bed'hom B, 2013. Diversity and evolution of the highly polymorphic tandem repeat LEI0258 in the chicken MHC-B region. Immunogenetics, 6, 447-459, doi 10.1007/s00251-01 0697-6

Wang Yq., Gao Y., Imsland F., Gu Xr., Feng Cg., Liu Rr., Song C.,  Tixier-Boichard M., Gourichon D., Li Qy., Chen Kw., Li Hf., Andersson L., Hu Xx., Li N., 2012. The Crest phenotype in chicken is associated with ectopic expression of HOXC8 in cranial skin. PLoS One 7(4): e34012   doi: 10.1371/journal.pone.0034012

Leroy G., Kayang B.B., Youssao I.A.K., Yapi-Gnaore C.V., Osei-Amponsah R., Loukou N.E., Fotsa J.C., Benabdeljelil K., Bed'hom B., Tixier-Boichard M., Rognon X., 2012 Gene diversity, agroecological structure and introgression patterns among village chicken populations across North West and Central Africa. BMC Genetics, 13:34

Imsland F., Feng Cg., Boije H., Bed’hom B., Fillon V., Dorshorst B., Rubin Cj., Liu Rr., Gao Y., Gu Xr., Wang Yq., Gourichon D., Zody Mc., Zecchin W., Vieaud A., Tixier-Boichard M., Hu Xx., Hallbook F., Li N., Andersson L., 2012. The rose-comb mutation in chickens constitutes a structural rearrangement causing both altered comb morphology and defective sperm motility. PLoS Genetics, 8 (6): e1002775. doi:10.1371/journal.pgen.1002775

Boije H., Harun-Or-Rashid M., Lee Yj., Imsland  F., Bruneau N., Vieaud A., Gourichon D., Tixier-Boichard M., Bed'hom B., Andersson L, Hallböök F., 2012. Sonic hedgehog-signalling patterns the developing chicken comb as revealed by exploration of the Pea-comb mutation. PLoS One, 10.1371/journal.pone.0050890

Youssao I.A. K., Senou M., Dahouda M., Idrissou N. D., Amoussou-Sydol E., Tougan U. P., Ahounou S., Yapi-Gnaore V. , Kayang B., Rognon X., Tixier-Boichard M. Kpodekon M. T. 2011. Laying performances and egg quality characteristics of  F1 crossbred hens resulting from Label Rouge (T55XSA51) and two local ecotypes as parental lines.  International J.  Livestock Production, 2, 69-78

Tixier-Boichard M., Bed’hom B., Rognon X. 2011. Chicken domestication : from archeology to genomics. C.R. Biologies 334, 197-204.

Mou C., Pitel F., Gourichon D., Vignoles F., Tzika A., Tato P., Yu L., Burt D.W., Bed’hom B.,Tixier-Boichard M., Painter K.J., Headon D., 2011. Cryptic patterning of avian skin confers a developmental facility for loss of neck feathering. PLoS Biology, 9(3): e1001028. doi:10.1371/journal.pbio.1001028

Boettcher P.J., Tixier-Boichard M., Toro M.A., Simianer H., Eding H., Gandini G., Joost S., Garcia D., Colli L., Ajmone-Marsan P. and the GLOBALDIV consortium, 2010. Objectives, criteria and methods for using molecular genetic data in priority setting for conservation of animal genetic resources. Animal Genetics, 41, Suppl 1, 64-77.

Hellström AR, Sundström E, Gunnarsson U, Bed'hom B, Tixier-Boichard M, Honaker CF, Sahlqvist AS, Jensen P, Kämpe O, Siegel PB, Kerje S, Andersson L., 2010. Sex-linked barring in chickens is controlled by the CDKN2A /B tumour suppressor locus. Pigment Cell Melanoma Res. 23, 521-530.

Osei-Amponsah R., Kayang B.B., Naazie A., Osei Y.D., Tixier-Boichard M., Rognon X., 2010. Genetic diversity of Forest and Savannah chicken populations of Ghana as estimated by microsatellite markers. Animal Science Journal., 81, 297-303.

Rubin,C.-J., Zody,M.C., Eriksson,J., Meadows,J.R.S., Sherwood,E., Webster,M.T., Jiang,L., Ingman,M., Sharpe,T., Ka,S., Hallböök,F., Besnier,F., Carlborg,Ö., Bed’hom,B., Tixier-Boichard,M., Jensen,P., Siegel,P., Lindblad-Toh,K. and Andersson, L. 2010. Whole genome resequencing reveals loci under selection during chicken domestication. Nature 464: 587-591

Chen C.F., Gourichon D., Huang N.Z., Lee Y.P., Bordas A., Tixier-Boichard M., 2009. Performance comparison of dwarf laying hens segregating for the naked neck gene in temperate and subtropical environments. Genetics Selection Evolution 2009, 41:13

Berthouly, C., B. Bed'Hom, M. Tixier-Boichard, C. F. Chen, Y. P. Lee, D. Laloe, H. Legros, E. Verrier, X. Rognon. 2008. Using molecular markers and multivariate methods to study the genetic diversity on local European and Asian chicken breeds. Animal Genetics 39:121-129

Eriksson J., Larson G., Gunnarsson U., Bed'hom B., Tixier-Boichard M., Stromstedt L., Wright D., Jungerius A., Vereijken A., Randi E., Jensen P., Andersson L., 2008. Identification of the Yellow Skin gene reveals a hybrid origin of the domestic chicken. PLoS Genet, 4, e1000010

Tixier-Boichard M., Ayalew W., Jianlin H., 2008. Inventory, characterisation and monitoring of animal genetic resources. Animal Genetic Resources Information, 42, 29-47.

Blesbois E., Seigneurin F., Grasseau I., Limouzin C., Besnard J., Gourichon D., Coquerelle G., Rault P., Tixier-BOICHARD M. 2007. Semen cryopreservation for ex-situ management of genetic diversity in chickens : creation of the French Avian Cryobank. Poultry Science . 86, 555-564.

Other productions :

Tixier-Boichard M., Bouvier E., Duclos M., Geraert P-A., Lessire M., Magnin M., 2012. Dossier de candidature de la branche française de la WPSA pour l’organisation du congrès mondial d’aviculture à Paris en 2020.  41 pages

Tixier-Boichard M., De Renty P., 2014. Compte-rendu scientifique 2013 Infrastructure CRB-Anim du programme Investissements d’Avenir. 8 pages.

Tixier-Boichard M., 2014. Partage des données relatives aux ressources génétiques et génomiques : état des lieux, analyse stratégique et besoins d’accompagnement. Rapport du groupe de travail ‘ressources génomiques’ du chantier INRA ‘open data’.  10 pages. Membres du groupe : P. Bessières, S. Carrère, S. Casaregola, G. Lassalle, F. Legeai, N. Mohellibi, F. Moreews, J-L. Noyer, H. Quesneville, L. Ranjard, S. Sidibe-Bocs,

Tixier-Boichard M., Moroldo M., Bevilacqua C., Martin P., Bouet S., Vincent-Naulleau S., 2013. @BRIDGe : @nimal Biological Resources for Integrative and Digital Genomics. Dossier de labellisation CNOC, 24 pages